Publications

- Maturana C. J. & Engel E. A. (2024). Persistent transgene expression in peripheral tissues one year post intravenous and intramuscular administration of AAV vectors containing the alphaherpesvirus latency-associated promoter 2. Frontier in Virology, 4

- Maturana, C. J., (2023). Engineered compact pan-neuronal promoter from Alphaherpesvirus LAP2 enhances target gene expression in the mouse brain and reduces tropism in the liver. Gene Therapy, 1-10

 - Maturana, C. J., Chan, A., Verpeut, J. L., & Engel E. A. (2023). Local and systemic administration of AAV vectors with alphaherpesvirus latency-associated promoter 2 drives potent transgene expression in mouse liver, kidney, and skeletal muscle. Journal of Virological Methods, 314, 114688

- Chan, A., Maturana, C. J., & Engel, E. A. (2022). Optimized formulation buffer preserves Adeno-associated virus-9 infectivity after 4°C storage and freeze/thawing cycling. Journal of Virology Methods, 309, 114598

- Bravo, D., Zepeda-Morales, K., Maturana, C. J., Retamal, J. S., Hernández, A., Pelissier, T., … & Constandil, L. (2022). NMDA and P2X7 receptors require pannexin 1 activation to initiate and maintain nociceptive signaling in the spinal cord of neuropathic rats. International Journal of Molecular Sciences, 23(12), 6705

- Maturana, C. J., Verpeut, J. L., & Engel, E. A. (2022). Single-Cell Quantification of Triple-AAV Vectors Genome Coexpressed in Neurons. Current Protocols, 2(5), e430

- Maturana, C. J., Verpeut, J. L., Kooshkbaghi, M., & Engel E. A. (2021). Novel tool to quantify with single-cell resolution the number of incoming AAV genomes co-expressing in the mouse nervous system. Gene Therapy, 30, 463–468

- Laval, K., Maturana, C. J., & Enquist, L. W. (2020). Mouse Footpad Inoculation Model to Study Viral-Induced Neuroinflammatory Responses. JoVE (Journal of Visualized Experiments), (160), e61121

- Maturana, C. J., Verpeut, J. L., Pisano, T. J., Dhanerawala, Z. M., Esteves, A., Enquist, L. W., & Engel, E. A. (2020). Small Alphaherpesvirus Latency-Associated Promoters Drive Efficient and Long-Term Transgene Expression in The Central Nervous System. Molecular Therapy-Methods & Clinical Development, 17, 843-857

- Gómez, G. I., Falcón, R. V., Maturana, C. J., Labra, V. C., Salgado, N., Rojas, C. A., ... & Orellana, J. A. (2018). Heavy alcohol exposure activates astroglial hemichannels and pannexons in the hippocampus of adolescent rats: effects on neuroinflammation and astrocyte arborization. Frontiers in cellular neuroscience, 12, 472

- Wellmann, M., Álvarez-Ferradas, C., Maturana, C. J., Sáez, J. C., & Bonansco, C. (2018). Astroglial Ca2+dependent hyperexcitability requires P2Y1 purinergic receptors and pannexin-1 channel activation in a chronic model of epilepsy. Frontiers in cellular neuroscience, 12, 446

- Maturana, C. J., Aguirre, A., & Sáez, J. C. (2017). High glucocorticoid levels during gestation activate the inflammasome in hippocampal oligodendrocytes of the offspring. Developmental neurobiology, 77(5), 625-642

- Gajardo‐Gómez, R., Labra, V. C., Maturana, C. J., Shoji, K. F., Santibañez, C. A., Sáez, J. C., ... & Orellana, J. A. (2017). Cannabinoids prevent the amyloid β‐induced activation of astroglial hemichannels: A neuroprotective mechanism. Glia, 65(1), 122-137

- Bravo, D., Maturana, C. J., Pelissier, T., Hernandez, A., & Constandil, L. (2015). Interactions of pannexin 1 with NMDA and P2X7 receptors in central nervous system pathologies: Possible role on chronic pain. Pharmacological research, 101, 86-93

- Orellana, J. A., Moraga-Amaro, R., Díaz-Galarce, R., Rojas, S., Maturana, C. J., Stehberg, J., & Sáez, J. C. (2015). Restraint stress increases hemichannel activity in hippocampal glial cells and neurons. Frontiers in cellular neuroscience, 9, 102

- Aguirre, A., Maturana, C. J., Harcha, P. A., & Sáez, J. C. (2013). Possible involvement of TLRs and hemichannels in stress-induced CNS dysfunction via mastocytes, and glia activation. Mediators of inflammation, 2013